Scientific Associate

BioPhase Solutions specializes in recruiting top talented professionals for San Diego's Scientific community. We are currently looking for a Scientific Associate to work for a leading San Diego biotechnology company.


Scientific Associate


Position Responsibilities:
  • Assist the Associate Scientists and Scientists with the technical transfer of downstream manufacturing processes from clients and between Process Development and Manufacturing groups.
  • Assist in scale-up calculations for varying scales of the process – up to cGMP scale. 
  • Assists in the purification of proteins to support lead generation/optimization and preclinical studies.
  • Assists in producing purified proteins under cGMP standards for production of clinical trial materials as necessary.
  • Weighs, measures and checks raw materials to assure proper ingredients and quantities. 
  • Prepare solutions:
    • Buffers, media
    • Aliquot solutions, including aseptically aliquoting sterile reagents
    • Assay solutions
  • Prepare items for sterilization, to include autoclaving and dry heat. 
  • Assist with sample/product analysis:
    • Sampling raw materials for analysis
    • Running SDS-PAGE (coomassie gels, Western blots)
    • Nova biochemistry analysis
    • Spectrophotometric assays
  • Assist manufacturing in protein purification and manufacturing of final products. 
  • Assists manufacturing in production-scale operations.
  • Proper documentation of observations and collecting data for analysis.  
  • Conduct activities in support of production schedules and objectives as directed by senior staff.
  • Orders process materials needed for varying scales of the process with consideration of scale-up calculations. 
  • Maintains records to comply with good documentation practices and assist with in-process testing.

Responsibilities:
  • Maintains records to comply with regulatory requirements and assists with in-process testing.
  • Obtains and stocks supplies as directed. 
  • Maintain proper laboratory cleanliness and organization 
  • Adhere to all safety standards and protocols 
  • Operates to the highest ethical and moral standards.
  • Complies with company policies and procedures.
  • Adheres to quality standards set by regulations and company policies, procedures and mission.
  • Communicates effectively with supervisors, colleagues and subordinates. 
  • Ability to participate effectively as a team player in all aspects of the business.
  • Demonstrated administrative leadership with knowledge-based expertise in related areas that can be applied to meeting company strategic goals.
  • Travels as needed to attend professional conferences, train on new technologies, and execute process transfer in support of clients. 

Requirements:
  • BA/BS degree in a science related field that included laboratory work in a chemistry, biology, chemical engineering or related field plus 1-3 years of relevant experience in a cGMP manufacturing/laboratory environment. 
  • Basic knowledge of protein purification.
  • Skilled with and single-use technologies.
  • Ability to follow detailed instructions and to maintain accurate records and notes. 
  • Ability to work effectively in a team environment.
  • Ability to prioritize and successfully perform multiple tasks.
  • Skills in problem solving and troubleshooting.
  • Ability to safely operate production equipment in accordance with established practices.

  • Location: San Diego
  • Type: Permanent
  • Job ID: BR4779361215